New Parameters of Hemostasis, some of their Research Results during Pregnancy

Abstract

The article presents up-to-date information about the hemostasis system is a biological system that ensures the preservation of the liquid state of the blood, maintaining the integrity of the walls of blood vessels, preventing and stopping bleeding from the latter by thrombosis. Hemostasis is implemented mainly by three interacting functional and structural components: the walls of blood vessels (primarily intima), blood cells (platelets, erythrocytes, etc.) and plasma enzyme systems (coagulation, fi brinolytic, kallikrein-kinin, etc.). The article presents data from original studies of 20 women with their fi rst pregnancy between the ages of 25 and 28 (the gestation period was 18 to 20 weeks). And 10 non-pregnant women (control group). We studied the aggregation of enterocytes and to study the aggregation of platelet aggregation (Rheoscan apparatus). Further, by transforming the data with the technical analysis program (Tas-Plus apparatus), we calculated the platelet and erythrocyte aggregation indexes (PAI and EAI). The research was conducted in accordance with the Declaration of Helsinki. Pregnant and healthy control women were notifi ed of the study. We have received informational consent from them. Our statistical data showed that the aggregation of erythrocytes (EAI) is increased in comparison with the norm by 15% (*), the aggregation of platelets (PAI) is increased in comparison with the norm by 25% (*).