The impact of vaccination on COVID-19

Abstract

The coronavirus disease 2019 (COVID-19) pandemic caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) became a challenge globally by affecting millions of people worldwide. COVID-19 vaccination is an effective option to stop disease outbreak. COVID-19 vaccines are fully approved or currently authorized for use through Emergency Use Authorization (EUA) from the Food and Drug Administration (FAD) are essential for controlling the COVID-19 pandemic. Despite COVID-19 vaccines are effective, some fully vaccinated persons can be infected with SARS-CoV-2 called breakthrough infection. Observing COVID-19 results in populations by vaccination status is simplififi ed through dependable correlation of COVID-19 case surveillance and vaccination data. The incidence of SARS-CoV-2 infection, hospitalization, and death is elevated in unvaccinated than vaccinated persons, and the incidence rate ratios are related to vaccine effectiveness. We conducted a retrospective analysis of medical reports of 169 patients with confifirmed COVID-19. We assessed vaccine effectiveness against COVID-19 and against hospitalization with COVID-19 in the Infectious Disease, AIDS and Clinical Immunology Research Centre, Georgia from from April 1 through October 31, 2021. Our study indicates the vaccine effectiveness against COVID-19. Hospitalization rate were higher in unvaccinated patients compared with vaccinated patients. Vaccination is considered to be one of the most important advances in public health. There are many people who are not vaccinated. It is important to create the awareness about COVID-19 vaccines and educate people about the importance of vaccine and its effectiveness.