Mifepriston fore safe pregnancy termination in 2nd trimester

Abstract

Mifepristone has been developed to antagonize the action of progesterone, and has a recognized role in the medical termination of pregnancy. Its medical effects reflfl ect not only on pregnancy termination during the fifi rst weeks, but successfully may be used for induction of abortion in the second trimester of pregnancy and for labor induction. Additionally, Mifepristone may be effective as pain arrest medicine during labor. Determining the role of Mifepristone in cervix ripening in the second-trimester pregnancy termination and evaluating its effifi cacy as pain killer medicine. The research included 19-41 years old 195 women with the need for pregnancy termination in the second trimester. The groups we divided into mifepristone and Folly balloon groups, used as a control. Mifepristone was used in an attempt at cervical ripening. The effifi cacy of Mifepristone was assessed using the degree of cervical ripening and by the scale of pain severity (APS). In the Mifepristone group the patients stay in the hospital was reduced compared to the folly balloon group. The pain score was signififi cantly low in patients using Mifepristone as a painkiller medicine. In main group the pain level with mi was 4,5-5 and with a folly balloon – 7,9-9. Mifepristone is effective in maturing the cervix for late abortion and for labor. Considering the lack of cases, the studies must be continued in this connection.